Lung Development Genes and Adult Lung Function
نویسندگان
چکیده
منابع مشابه
Role of Lung Function Genes in the Development of Asthma
Although our previous GWAS failed to identify SNPs associated with pulmonary function at the level of genomewide significance, it did show that the heritability for FEV1/FVC was 41.6% in a Japanese population, suggesting that the heritability of pulmonary function traits can be explained by the additive effects of multiple common SNPs. In addition, our previous study indicated that pulmonary fu...
متن کاملReduced Lung Function and Progression to Prediabetes: A Prospective Study
Objective: Prediabetes is a state that people have blood glucose levels higher than normal but still not in diabetes range. There is a close relationship between impaired lung function and diabetes mellitus (DM). Reduced lung function can be present before the clinical evidence of diabetes or insulin resistance. Materials and Methods: The total number of subjects in this longitudinal study was ...
متن کاملBirth weight and adult lung function.
Since the maximum possible score becomes 7, we defined severe pneumonia as a score >4 for the CURB-age criteria compared with >3 for CURB-65. The subjects were 189 patients (median age 75 years, range 17–96, 56.1% men) who were included in two prospective observational studies of CAP. Detailed methodology has been reported previously. 5 Using CURB-65 there were 109 non-severe cases (57.7%) and ...
متن کاملBirth weight and adult lung function
Since the maximum possible score becomes 7, we defined severe pneumonia as a score >4 for the CURB-age criteria compared with >3 for CURB-65. The subjects were 189 patients (median age 75 years, range 17–96, 56.1% men) who were included in two prospective observational studies of CAP. Detailed methodology has been reported previously. 5 Using CURB-65 there were 109 non-severe cases (57.7%) and ...
متن کاملGenes associated with polymorphic variants predicting lung function are differentially expressed during human lung development
BACKGROUND Recent meta-analyses of genome-wide association studies have identified single nucleotide polymorphisms (SNPs) within/near 54 genes associated with lung function measures. Current understanding of the contribution of these genes to human lung development is limited. We set out to further define i) the expression profile of these genes during human lung development using a unique set ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2020
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.201912-2338oc